
2019年9月27日,『生命有機化學國家重點實驗室』和香港理工大學『化學生物學和藥物發(fā)現(xiàn)國家重點實驗室』在上海有機所舉行了第九屆伙伴實驗室年度學術(shù)交流會議。
在為期一天的工作交流中,共有20位研究人員分別就各自課題組的研究方向以及近期的研究進展做了介紹。與會學者探討了相關(guān)的科學問題和技術(shù)手段,就研究細節(jié)提出了積極的建議,并對化學生物學的合作研究進行了深入討論。
學術(shù)報告如下:
1.Total Synthesis and Structural Revision of Miharamycins and Amipurimycin(Prof. Biao Yu)
2.Development of Inhibitors for Peptidoglycan Glycosyltransferase in Bacterial Cell Wall Synthesis(Prof. Kwok-yin Wong)
3.A KAS-III Heterodimer in Lipstatin Biosynthesis(Prof. Wen Liu)
4.Development of Arginase for Cancer Treatment(Prof. Thomas Y.C. Leung)
5.Biosynthesis, Combinatorial Biosynthesis, and Genome Mining of Complex Aromatic Polyketides(Prof. Gongli Tang)
6.Photoredox Decarboxylative C(sp3)-N Coupling of alpha-Diazoacetates with Alkyl N-Hydroxyphthalimide Esters for Diversified Synthesis of Functionalized N-Alkyl Hydrazones(Dr. Wing-yiu Yu)
7.Biocompatible Visible-Light-Induced Chemistry(Prof. Yiyun Chen)
8.Asymmetric Gold Catalysis and Synthetic Utility of Propargylamines(Dr. Man Kin Wong)
9.Chemical Proteomics for Drug Discovery(Dr. Qian Zhao)
10.Imaging of DNA G-Quadruplex Structures in Living Cells with Fluorescent Binding Ligands(Dr. Wing-Leung Wong)
11.Potentially Recognization of Oncogene RET G4-DNA by Natural Product Colchicine(Prof. Chunyang Cao)
12.Ligand-Enabled Cross-Coupling Reactions of C-O Electrophiles and Its Potential Application Towards Drugs Discovery(Dr. Chau-ming So)
13.Structural Characterizations of the Autophagic SNARE Proteins(Prof. Lifeng Pan)
14.CCCTC-Binding Factor (CTCF) as a Novel Therapeutic Target for Hepatocellular Carcinoma(Dr. Chi-Bun Ko)
15.Probing Interactomes and Drug Targets by Affinity Purification Coupled with Quantitative Proteomics(Prof. Jingwu Kang)
16.Supramolecular Transformation of Lanthanide Helicates and Cages with C2-Symmetric Ligands(Dr. Chi-tung Yeung)
17.Modulating MiTFactiviy Through Small Molecular Compounds by Nature and by Us(Prof. Jing Wang)
18.Deriving Antimicrobial Peptides from S. aureus Toxins(Dr. Kin Fai Cha)
19.Multiple Reasons to Develop Aminoacyl-tRNA Synthetase Inhibitors (Prof. Pengfei Fang)
20.Recent Progress in Asymmetric Cross-Coupling(Prof. Wenjun Tang)

圖一:參會代表合影
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