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姓 名: |
張新剛 |
性 別: |
男 |
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職 稱: |
研究員 |
學 歷: |
博士研究生 |
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電 話: |
021-54925333 |
傳 真: |
021-64166128 |
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電子郵件: |
xgzhang@mail.sioc.ac.cn |
個人主頁: |
http://xgzhang.sioc-f.cn/ |
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通訊地址: |
上海市零陵路345號 200032 |
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| 簡歷: |
1998年畢業(yè)于四川大學應用化學系;2003年獲中科院上海有機化學研究所理學博士學位;之后在美國伊利諾伊大學香檳分校(University of Illinois at Urbana-Champaign, UIUC)化學系Wilfred A. van der Donk課題組從事博士后及研究助理,研究領域為化學生物學;2008年5月任上海有機化學研究所創(chuàng)新崗位副研究員,課題組長,研究生導師;2012年1月起任研究員,博士生導師。 |
| 研究方向: |
金屬有機氟化學:以過渡金屬催化為手段,研究廉價易得的含氟工業(yè)原料和工業(yè)廢棄物的高效轉化,使之具有工業(yè)應用前景,建立高效廉價金屬催化體系,發(fā)展高效溫和的氟化新策略、新反應和新方法; 化學生物學相關研究:應用化學生物學手段以及氟原子的獨特反應性發(fā)展對多肽、蛋白、核酸進行選擇性修飾的方法,并進一步應用到化學生物學及相關領域中。 |
| 獲獎及榮譽: |
2017年 “萬人計劃”科技創(chuàng)新領軍人才 2016年 科技部中青年科技創(chuàng)新領軍人才 2015年 RSC Fluorine Chemistry Prize(英國皇家化學會氟化學獎) 2015年 第五屆中國化學會—英國皇家化學會青年化學家獎 2014年 國家“杰出青年科學基金” 2014年 Thieme Chemistry Journal Award 2014 2009年 上海市“青年科技啟明星”計劃 |
| 代表論著: |
1.Chang Xu,Wen-Hao Guo,Xu He, Ying-Long Guo, Xue-Ying Zhang, and Xingang Zhang*, “Difluoromethylation of (Hetero)Aryl Chlorides with Chlorodifluoromethane Catalyzed by Nickel”, Nat. Commun. 2018, Accepted. 2.Xing Gao, Yu-Lan Xiao, and Xingang Zhang*, “Copper-Catalyzed Highly Stereospecific Trifluoromethylation and Difluoroalkylation of Secondary Propargyl Sulfonates” Angew. Chem. Int. Ed. 2018, DOI: 10.1002/anie.2017114673. 3.Zhang Feng,? Qiao-Qiao Min,? Xia-Ping Fu,? Lun An, and Xingang Zhang,* “Chlorodifluoromethane-Triggered Formation of Difluoromethylated Arenes Catalysed by Palladium”, Nature Chemistry, 2017, 9, 918 (This paper was highlighted by Chemical & Engineering News 2017, 95, 7; ACS Molecule of the week June 19, 2017; Synfacts 2017, 13, 1126). 4.Ji-Wei Gu, Qiao-Qiao Min, Ling-Chao Yu, and Xingang Zhang,* “Tandem Difluoroalkylation-Arylation of Enamides Catalyzed by Nickel” Angew. Chem. Int. Ed. 2016, 55, 12270-12274. 5.Wen-Hao Guo, Qiao-Qiao Min, Ji-Wei Gu, and Xingang Zhang,* “Rhodium-Catalyzed ortho-Selective C-F Bond Borylation of Polyfluoroarenes with Bpin-Bpin” Angew. Chem.Int. Ed. 2015, 54, 9075. 6.Yu-Lan Xiao, Wen-Hao Guo, Guo-Zhen He, Qiang Pan, and Xingang Zhang,* “Nickel-Catalyzed Cross-Coupling of Functionalized Difluoromethyl Bromides and Chlorides with Aryl Boronic Acids: A General Method for Difluoroalkylated Arenes” Angew. Chem. Int. Ed. 2014, 53, 9909 (This paper was highlighted by Chemical & Engineering News 2014, 92, 25). 7.Zhang Feng, Qiao-Qiao Min, Yu-Lan Xiao, Bo Zhang, and Xingang Zhang,* “Pd-Catalyzed Difluoroalkylation of Arylboronic Acids: A New Method for Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives” Angew. Chem., Int. Ed. 2014, 53, 1669 (This paper was highlighted by Chemical & Engineering News 2014, 92, 25) 8.Qiao-Qiao Min, Zengsheng Yin, Zhang Feng, Wen-Hao Guo, and Xingang Zhang,* “Highly Selective gem-Difluoroallylation of Organoborons with Bromodifluoromethylated Alkenes Catalyzed by Palladium” J. Am. Chem. Soc. 2014, 136, 1230. 9.Xingang Zhang*, Shilu Fan, Chun-Yang He, Xiaolong Wan, Qiao-Qiao Min, Jie Yang and Zhong-Xing Jiang, “Pd(OAc)2 Catalyzed Olefination of Highly Electron-deficient Perfluoroarenes” J. Am. Chem. Soc. 2010, 132, 4506. (This paper was highlighted in Synfacts, 2010, 6, 0652) 10.Chun-Yang He, Shilu Fan, and Xingang Zhang,* “Pd-Catalyzed Oxidative Cross-Coupling of Perfluoroarenes with Aromatic Heterocycles” J. Am. Chem. Soc. 2010, 132, 12850. |
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