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姓 名: |
洪然 |
性 別: |
男 |
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職 稱: |
研究員 |
學(xué) 歷: |
研究生 |
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電 話: |
021-54925161 |
傳 真: |
021-64166128 |
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電子郵件: |
rhong@mail.sioc.ac.cn |
個(gè)人主頁: |
http://honggroup.sioc.ac.cn |
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通訊地址: |
上海市零陵路345號(hào) 200032 |
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| 簡(jiǎn)歷: |
1992–1996,四川大學(xué), 物理化學(xué),本科 1996–2001, 中科院上海有機(jī)所,理學(xué)博士, 導(dǎo)師: 林國強(qiáng) 研究員 2001–2002, University of Houston, 博士后, 導(dǎo)師:Prof. Jay K. Kochi 2002–2007, Brandeis University, 博士后, 導(dǎo)師:Prof. Li Deng 2007–至今,中科院上海有機(jī)所, 研究員, 課題組長(zhǎng) |
| 研究方向: |
天然產(chǎn)物仿生合成、酶催化和不對(duì)稱合成方法。致力于將生物合成的策略應(yīng)用于反應(yīng)方法學(xué)的發(fā)展和具有重要生理活性的復(fù)雜天然產(chǎn)物全合成研究。 |
| 獲獎(jiǎng)及榮譽(yù): |
上海市青年科技啟明星 (2008) “中國化學(xué)會(huì)維善天然產(chǎn)物合成化學(xué)獎(jiǎng)” (2017) Thieme Chemistry Journal Award (2018) ACP Lectureship Award (2015-臺(tái)灣, 2016-日本, 2016-馬來西亞, 2017-新加坡) |
| 代表論著: |
1. Lin Yang, Zuming Lin, Shunjie Shao, Qian Zhao, and Ran Hong*, “Enantioconvergent and Concise Synthesis of Lasonolide A” Angew. Chem., Int. Ed. 2018, 57, Early View, DOI:10.1002/anie.201811093. 2. Changmin Xie, Jisheng Luo, Yuping Zhang, Sha-Hua Huang, Lili Zhu, and Ran Hong*, "Catalytic Aza-Wacker Annulation: Tuning Mechanism by the Activation Mode of Amide and Enantioselective Syntheses of Melinonine-E and Strychnoxanthine" Org. Lett. 2018, 20, 2386?2390. 3. Kuan Zheng, Defeng Shen, Ran Hong*, "Bioimetic Synthesis of Lankacidin Antibiotics" J. Am. Chem. Soc. 2017, 139, 12939?12942. 4. Li Zhai, Xuechao Tian, Chao Wang, Qi Cui, Wenhua Li, Sha-Hua Huang*, Zhi-Xiang Yu*, Ran Hong*, "Construction of Morphan Derivatives by Nitroso-Ene Cyclization: Mechanistic Insight and Total Synthesis of (±)-Kopsone" Angew. Chem., Int. Ed. 2017, 56, 11599?11603. 5. Lin Yang, Zuming Lin, Sha-Hua Huang*, Ran Hong*, "Stereodivergent Synthesis of Functionalized Tetrahydropyrans Accelerated by Mechanism-Based Allylboration and Bioinspired oxa-Michael Cyclization" Angew. Chem., Int. Ed. 2016, 55, 6280?6284. 6. Jie Ouyang, Rui Yan, Xianwei Mi, Ran Hong*, "Enantioselective Total Synthesis of (?)-Hosieine A" Angew. Chem., Int. Ed. 2015, 54, 10940?10943. 7. Lin Yang, Guoli He, Ruifeng Yin, Lili Zhu, Xiaoxia Wang, Ran Hong*, "Synthesis of Polyketide Stereoarrays Enabled by A Traceless Oxonia–Cope Rearrangement" Angew. Chem., Int. Ed. 2014, 53, 11600?116004. 8. Lili Zhu, Jisheng Luo, Ran Hong*, "Total Synthesis of (±)-Cafestol: A Late-Stage Construction of the Furan Ring Inspired by A Biosynthesis Strategy" Org. Lett. 2014, 16, 2162?2165. 9. Yan Wang, Kuan Zheng, Ran Hong*, "Chiral Silver Phosphate-catalyzed Cycloisomeric Kinetic Resolution of α-Allenic Alcohols" J. Am. Chem. Soc. 2012, 134, 4096?4099. 10.Yan Wang, Lili Zhu, Yuying Zhang, Ran Hong*, "Bioinspired and Concise Synthesis of (±)-Stemoamide" Angew. Chem., Int. Ed. 2011, 50, 2787?2790. |
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