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姓 名: |
殷亮 |
性 別: |
男 |
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職 稱(chēng): |
研究員 |
學(xué) 歷: |
博士研究生 |
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電 話(huà): |
021-54925168 |
傳 真: |
021-64166128 |
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電子郵件: |
liangyin@sioc.ac.cn |
個(gè)人主頁(yè): |
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通訊地址: |
上海市零陵路345號(hào) 200032 |
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| 簡(jiǎn)歷: |
2000.09—2004.06 南開(kāi)大學(xué)化學(xué)學(xué)院本科 2004.09—2007.06 南開(kāi)大學(xué)化學(xué)學(xué)院碩士研究生 2007.10—2010.09 日本東京大學(xué)藥學(xué)部博士課程 (Prof. Masakatsu Shibasaki and Prof.Motomu Kanai) 2010.10—2011.03 日本東京大學(xué)藥學(xué)部JSPS博士后 (Prof. Motomu Kanai) 2011.04—2012.03 美國(guó)哈佛大學(xué)化學(xué)與化學(xué)生物學(xué)系博士后 (Prof. E. J. Corey) 2012.04—2014.10 日本微生物化學(xué)研究所JSPS外國(guó)人博士后 (Prof. Masakatsu Shibasaki and Dr. Naoya Kumagai) 2014.10—至今 中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所研究員、課題組長(zhǎng) |
| 研究方向: |
新型簡(jiǎn)單易得手性配體和有機(jī)小分子催化劑的設(shè)計(jì)與合成 新型不對(duì)稱(chēng)催化反應(yīng)的開(kāi)發(fā)與應(yīng)用 具有重大生物活性的天然產(chǎn)物的全合成以及相關(guān)合成類(lèi)似物的藥物化學(xué)篩選 |
| 獲獎(jiǎng)及榮譽(yù): |
1.2007南開(kāi)大學(xué)優(yōu)秀碩士畢業(yè)論文一等獎(jiǎng) 2.2007日本政府文部科學(xué)省獎(jiǎng)學(xué)金 3.2010日本學(xué)術(shù)振興會(huì)JSPS博士和博士后獎(jiǎng)學(xué)金(DC2和PD) 4.2012日本學(xué)術(shù)振興會(huì)JSPS外國(guó)人博士后獎(jiǎng)學(xué)金 |
| 代表論著: |
1. Feng Zhong, Wen-Jun Yue, Hai-Jun Zhang, Cheng-Yuan Zhang, and Liang Yin* “Catalytic Asymmetric Construction of Halogenated Stereogenic Carbon Centers by Direct Vinylogous Mannich-Type Reaction” J. Am. Chem. Soc. 2018, 140, 15170–14175. 2. Hai-Jun Zhang, and Liang Yin* “Asymmetric Synthesis of ???-Unsaturated ?-Lactones through Copper(I)-Catalyzed Direct Vinylogous Aldol Reaction” J. Am. Chem. Soc. 2018, 140, 12270–12279. 3. Hai-Jun Zhang, Alexander W. Schuppe, Shi-Tao Pan, Jin-Xiang Chen, Bo-Ran Wang, Timothy R. Newhouse,* and Liang Yin* “Copper-Catalyzed Vinylogous Aerobic Oxidation of Unsaturated Compounds with Air” J. Am. Chem. Soc. 2018, 140, 5300–5310. 4. Hai-Jun Zhang, Chang-Yun Shi, Feng Zhong, and Liang Yin* “Direct Asymmetric Vinylogous and Bisvinylogous Mannich-Type Reaction Catalyzed by a Copper(I) Complex” J. Am. Chem. Soc. 2017, 139, 2196–2199. 5. Liang Yin, Lennart Brewitz, Naoya Kumagai,* and Masakatsu Shibasaki* “Catalytic Generation of ?-CF3 Enolate: Direct Catalytic Asymmetric Mannich-Type Reaction of ?-CF3 Amide” J. Am. Chem. Soc. 2014, 136, 17958–17961. 6. Liang Yin, Hisashi Takada, Shaoquan Lin, Naoya Kumagai,* and Masakatsu Shibasaki* “Direct Catalytic Asymmetric Vinylogous Conjugate Addition of Unsaturated Butyrolactones to ???-Unsaturated Thioamides” Angew. Chem. Int. Ed. 2014, 53, 5327–5331. 7. Liang Yin, Youmei Bao, Naoya Kumagai,* and Masakatsu Shibasaki* “Catalytic Asymmetric Hydrophosphonylation of Ketimines” J. Am. Chem. Soc. 2013, 135, 10338–10341. 8. Liang Yin, Hisashi Takada, Naoya Kumagai,* and Masakatsu Shibasaki* “Direct Catalytic Asymmetric Vinylogous Mannich-Type Reaction of ?-Butenolides with Ketimines” Angew. Chem. Int. Ed. 2013, 52, 7310–7313. 9. Liang Yin, Motomu Kanai* and Masakatsu Shibasaki* “A Facile Pathway to Enantiomerically-Enriched 3-Hydroxy-2-Oxindoles: Asymmetric Intramolecular Aryl-Transfer Reaction to Ketones Catalyzed by a Palladium-DifluorPhos Complex” Angew. Chem. Int. Ed. 2011, 50, 7620–7623. 10.Liang Yin, Motomu Kanai* and Masakatsu Shibasaki* “Nucleophile Generation via Decarboxylation: Asymmetric Construction of Contiguous Trisubstituted and Quaternary Stereocenters through a Cu(I)-Catalyzed Decarboxylative Mannich-Type Reaction” J. Am. Chem. Soc. 2009, 131, 9610–9611. |
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