1991.9-1995.7??南京理工大學化工學院，獲工學學士
1996.9-1999.8??中國科學院大連化學物理研究所，獲理學碩士
1999.9-2002.8??中國科學院上海有機化學研究所，獲理學博士
2003.3-2005.7??美國Lehigh大學，博士后
2005.8-2007.7??美國威斯康辛大學麥迪遜分?；瘜W系，研究助理
2007.7-至今????中國科學院上海有機化學研究所，研究員
過渡金屬催化烴類分子的選擇性轉化：重點圍繞金屬對自由基物種的調控機制，開展烷烴碳氫鍵的高位點、不對稱催化轉化，以及簡單烯烴的選擇性轉化及其相關應用研究。
2011年，中國化學會首屆均相催化青年獎
2012年，Thieme Chemistry Journal Award
2012年，國家基金委杰出青年基金獲得者
2012年，“Asian Core Program Lectureship Award”?Sponsored by?Singapore
2012年，“Asian Core Program Lectureship Award”?Sponsored by Japan
2014年，中國科學院“優(yōu)秀研究生指導教師”獎
2016年，科技部創(chuàng)新人才推進計劃-中青年科技領軍人才
2016年，中國科學院“朱李月華”優(yōu)秀教師獎
2017年，上海市領軍人才
2017年，上海市科委優(yōu)秀學術帶頭人
2017年，中國科學院優(yōu)秀導師獎
2018年，中國化學會-巴斯夫青年知識創(chuàng)新獎
2019年，德國洪堡基金會“Friedrich Wilhelm Bessel Research Award”
2019年，上海市自然科學獎一等獎 （排名第一）
2023年，騰訊新基石研究員項目
1.?Honggang Zhang, Yibo Zhou,? Tilong Yang, Jingui Wu, Pinhong Chen, Zhenyang Lin?,* Guosheng Liu?*?Site- and enantioselective allylic and?propargylic C–H oxidation enabled by?copper-based biomimetic catalysis. Nat. Catal. 2025, doi.org/10.1038/s41929-024-01276-4.
2.?Zhongming Cheng,#?Jiajun Zhang,#?Can Li, Xiang Li, Pinhong Chen, Guosheng Liu*?Copper-Catalyzed sp2?C-H Arylation and Alkynylation of Allenes via Hydrogen Atom Abstraction. J. Am. Chem. Soc. 2024, 146,?24689–24698.
3.?Xintuo Yang, Pinhong Chen, Guosheng Liu* Asymmetric 1,n-Remote Aminoacetoxylation of Unactivated Internal Alkenes Enabled by Palladium Catalysis. Angew. Chem. Int. Ed.?2024, 63, e202408305.
4.?Chuanqi Hou,#?Zhenye Liu,#?Lan Gan, Wenzheng Fan, Lin Huang, Pinhong Chen, Zheng Huang,?Guosheng Liu*?Palladium-Catalyzed Remote Hydrosulfonamidation of Alkenes:?Access to Primary N-Alkyl Sulfamides by the SuFEx Reaction. J. Am. Chem. Soc. 2024, 146,?13536–13545.
5.?Zhongming Cheng,?#?Tilong Yang,?#?Can Li,?#?Yunshun Deng, Fangjia Zhang, Pinhong Chen, Zhenyang Lin,*?Shengming Ma,*??Guosheng Liu*??Site-selective sp2?C-H Cyanation of Allenes via Copper-catalyzed Radical Relay.?J. Am. Chem. Soc. 2023, 145, 25995–26002.
6.?Liang Fu,#?Xin Chen,#?Wenzheng Fan, Pinhong Chen, Guosheng Liu*?Copper-Catalyzed Asymmetric Functionalization of Vinyl Radicals for the Access to Vinylarene Atropisomers.?J. Am. Chem. Soc.?2023,?145, 13476–13483.
7.?Xiaonan Li,?#?Tilong Yang,?#?Jiayuan Li, Xiang Li, Pinhong Chen, Zhenyang Lin*, Guosheng Liu*?Regio- and enantioselective remote dioxygenation of internal alkenes. Nat. Chem.?2023, 15, 862–871.
8.?Xiang Li, Xintuo Yang, Pinhong Chen,?Guosheng Liu*?Palladium-Catalyzed Remote Hydro-Oxygenation of Internal Alkenes: An Efficient Access to Primary Alcohols.?J. Am. Chem. Soc.?2022, 144, 22877–22883.
9.?Wenzheng?Fan,#?Xueyao?Zhao,#?Yunshun Deng, Pinhong Chen, Fei Wang,*?Guosheng Liu*?Electrophotocatalytic Decoupled Radical Relay Enables Highly Efficient and Enantioselective Benzylic C–H Functionalization. J. Am. Chem. Soc. 2022, 144, 21674–21682.
10.?Pin Xu, Wenzheng Fan, Pinhong Chen, Guosheng Liu*?Enantioselective Radical Trifluoromethylation of Benzylic C–H Bonds via Cooperative Photoredox and Copper Catalysis.?J. Am. Chem. Soc.?2022, 144, 13468–13474.
11.?Xintuo Yang, Xiang Li, Pinhong Chen,* Guosheng Liu* Palladium(II)-Catalyzed Enantioselective Hydrooxygenation of Unactivated Terminal Alkenes.?J. Am. Chem. Soc.?2022, 144, 7972–7977.
12.?Zuxiao Zhang,*?Pinhong Chen,?Guosheng Liu* Copper-catalyzed radical relay in C(sp3)–H functionalization. Chem. Soc. Rev.?2022,?51, 1640–1658.
13.?Xiang Li,#?Jianbo Jin,#?Pinhong Chen, Guosheng Liu*?Catalytic remote hydrohalogenation of internal alkenes. Nat. Chem.?2022, 14, 425–432.
14.?Fei Wang, Pinhong Chen, Guosheng Liu*?Copper-catalysed asymmetric radical cyanation. Nat. Synth.?2022, 1, 107–116.
15.?Ronghua Lu#, Tilong Yang#,?Xin Chen, Wenzheng Fan, Pinhong Chen,?Zhenyang Lin,*?Guosheng Liu*?Enantioselective Copper-Catalyzed Radical Cyanation of Propargylic C–H Bonds: Easy Access to Chiral Allenyl Nitriles. J. Am. Chem. Soc.?2021,?143,?14451–14457.
16.?Bing?Tian, Pinhong Chen, Xuebing Leng, Guosheng Liu*?Palladium-catalysed enantioselective diacetoxylation of terminal alkenes. Nat. Catal.?2021, 4, 172–179.
17.?Chao Jiang, Lei Wang, Honggang Zhang, Pinhong Chen,?Yin-Long Guo,?Guosheng Liu*?Enantioselective Copper-Catalyzed Trifluoromethylation of Benzylic Radicals via Ring Opening of Cyclopropanols. Chem. 2020, 6, 2407–2419.
18.?Guoyu Zhang#,?Song Zhou#,?Liang Fu, Pinhong Chen,?Yibiao Li,* Jianping Zou,*?Guosheng Liu*?Asymmetric Coupling of Carbon-Centered Radical Adjacent to Nitrogen: Copper-Catalyzed Cyanation and Etherification of Enamides. Angew. Chem. Int. Ed.?2020,?59, 20439–20444.
19.?Xiaonan Li,?Xiaoxu Qi, Chuanqi Hou,?Pinhong Chen,*?Guosheng Liu*?Palladium(II)-Catalyzed Enantioselective Azidation of Unactivated Alkenes. Angew. Chem. Int. Ed.?2020,?59, 17239–17244.
20.?Liang Fu#, Zhihan Zhang#, Pinhong Chen, Zhenyang Lin,*?Guosheng Liu*?Enantioselective Copper-Catalyzed Alkynylation of Benzylic C–H Bonds via Radical Relay.?J. Am. Chem. Soc.?2020,?142, 12493–12500.
21.?Jiayuan Li, Zhihan Zhang, Lianqian Wu, Wen Zhang, Pinhong Chen, Zhenyang Lin,* Guosheng Liu* Site-specific allylic C–H bond functionalization with a copper-bound N-centred radical. Nature?2019,?574, 516–521.
22.?Xiaonan Li, Pinhong Chen,?Guosheng Liu*?Iodine(III) reagent (ABX—N3)-induced intermolecular anti-Markovnikov hydroazidation of unactivated alkenes. Sci. China Chem.?2019, 62, 1537–1541.
23.?Wen Zhang, Lianqian Wu, Pinhong Chen, Guosheng Liu*?Enantioselective Arylation of Benzylic C-H Bonds by Copper-Catalyzed Radical Relay.?Angew. Chem. Int. Ed.?2019, 58, 6425–6429.
24.?Lianqian Wu, Fei Wang, Pinhong Chen,?Guosheng Liu* Enantioselective Construction of Quaternary All-Carbon Centers via Copper-Catalyzed Arylation of Tertiary Carbon-Centered Radicals.?J. Am. Chem. Soc.?2019, 141, 1887?1892.
25.?Fei Wang, Pinhong Chen, Guosheng Liu*?Copper-Catalyzed Radical Relay for Asymmetric Radical Transformations.?Acc.?Chem. Res.?2018, 51, 2036–2046.
26.?Liang Fu, Song Zhou, Xiaolong Wan, Pinhong Chen, Guosheng Liu*?Enantioselective Trifluoromethylalkynylation of Alkenes via Copper-Catalyzed Radical Relay.?J. Am. Chem. Soc.?2018, 140, 10965–10969.
27.?Xiaoxu Qi,#?Chaohuang Chen,#?Chuanqi Hou,?Liang Fu, Pinhong Chen, Guosheng Liu*?Enantioselective Pd(II)-Catalyzed Intramolecular Oxidative 6-endo Aminoacetoxylation of Unactivated Alkenes. J. Am. Chem. Soc.?2018, 140, 7415?7419.
28.?Chaohuang Chen,?Yixin Luo, Liang Fu, Pinhong Chen, Yu Lan,* Guosheng Liu*?Palladium-Catalyzed Intermolecular Ditrifluoromethoxylation of Unactivated Alkenes: CF3O?Palladation Initiated by Pd(IV).?J. Am. Chem. Soc.?2018, 140, 1207?1210.
29.?Dinghai Wang, Na Zhu, Pinhong Chen, Zhenyang Lin,*?Guosheng Liu*?Enantioselective Decarboxylative Cyanation Employing Cooperative Photoredox Catalysis and Copper Catalysis. J. Am. Chem. Soc.?2017, 139, 15632?15635.
30.?Wen Zhang, Pinhong Chen, Guosheng Liu* Copper-Catalyzed Arylation of Benzylic C–H bonds with Alkylarenes as the Limiting Reagents. J. Am. Chem. Soc. 2017, 139, 7709–7712.
31.?Dinghai Wang, Lianqian Wu, Fei Wang, Xiaolong Wan, Pinhong Chen, Zhenyang Lin*, Guosheng Liu* Asymmetric Copper-Catalyzed Intermolecular Aminoarylation of Styrenes: Efficient Access to Optical 2,2-Diarylethylamines.?J. Am. Chem. Soc. 2017,?139, 6811–6814.
32.?Lianqian Wu, Fei Wang, Xiaolong Wan, Dinghai Wang, Pinhong Chen,?Guosheng Liu* Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic Radicals. J. Am. Chem. Soc. 2017, 139, 2904–2907.
33.?Fei Wang, Dinghai Wang, Xiaolong Wan, Lianqian Wu, Pinhong Chen, Guosheng Liu* Enantioselective Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes via Radical Process. J. Am. Chem. Soc. 2016, 138, 15547–15550.
34.?Guoyin Yin, Xin Mu, Guosheng Liu* Palladium(II)-Catalyzed Oxidative Difunctionalization of Alkenes:Bond Forming at a High-Valent Palladium Center.?Acc. Chem. Res. 2016, 49, 2413?2423.
35.?Wen Zhang,=?Fei Wang,=?Scott D. McCann, Dinghai Wang, Pinhong Chen, Shannon S. Stahl,*?Guosheng Liu* Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay. Science?2016, 353, 1014–1018.
36.?Zheliang Yuan#, Ran Cheng#, Pinhong Chen, Guosheng Liu,* Steven Liang* Efficient Pathway for the Preparation of Aryl(isoquinoline)iodonium(III) Salts and Synthesis of Radiofluorinated Isoquinolines.?Angew. Chem. Int. Ed.?2016, 55,?11882–11886.
37.?Fei Wang, Dinghai Wang, Xin Mu, Pinhong Chen, Guosheng Liu*?Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+?Reagent. J. Am. Chem. Soc.?2014,?136, 10202–10205.
38.?Shuifa Qiu, Tao Xu, Juan Zhou, Yinlong Guo, Guosheng Liu* Palladium-Catalyzed Intermolecular Aminofluorination of Styrenes.?J. Am. Chem. Soc.?2010, 132, 2856–2857.
39.?Guoyin Yin, Yichen Wu, Guosheng Liu*?Scope and Mechanism of Allylic C?H Amination of Terminal Alkenes by the Palladium/PhI(OPiv)2?Catalyst System: Insights into the Effect of Naphthoquinone. J. Am. Chem. Soc. 2010, 132, 11978–11987.
40.?Tao Wu, Guoyin Yin, Guosheng Liu* Palladium-Catalyzed Intramolecular Aminofluorination of Unactivated Alkenes. J. Am. Chem. Soc.?2009, 131, 16354–16355.?
