1988.9.-1992.7.：湖南師范大學化學系，理學學士
1992.7.-1997.7.：湖南省邵陽師范高等?？茖W校，講師
1997.8.-2000.8.：上?；ぱ芯吭?，工學碩士
2000.8.-2003.7.：中國科學院上海有機化學研究所，理學博士
2003.8.-2005.7.：美國愛達荷大學，博士后研究
2005.8. 至今：中國科學院上海有機化學研究所，研究員，課題組長
1. 含氟試劑：從易得原料出發(fā)，設計新型含氟基團，發(fā)展溫和、高效的氟(烷基)化試劑
2. 氟化學反應：基于卡賓、葉立德等中間體的產生與轉化規(guī)律，探索新穎的(氟)化學反應
3. 萃取化學：闡明萃取劑分子結構與萃取性能之間的關系，發(fā)展綠色、高效的分離與純化方法
4. 高純氟鹽：研究高純氟化物、高純熔鹽的制備、性能與應用
1. Yang, Xin-Jun;?Wang, Zheng;?Ni, Qin-Yuan;?Lin, Jin-Hong*;?Xiao, Ji-Chang*?“Copper-Promoted Reductive Cross-Coupling for Cyanodifluoromethylation of (Hetero)aryl Iodides with BrCF2CN” Org. Lett.?2025, 27, 6867-6871.
2. Ni, Qin-Yuan;?Zhao, Shiyu;?Wu, Chengying;?Guo, Yong*;?Xiao, Ji-Chang*?“Synthesis of trans-2-(Disubstituted-amino)alkenyl Polyoxyperfluoroalkyl Ketones from Tertiary Amines and Perfluoroalkyl Ether Carboxylates Featuring "-CF2O-" Units” Chin. J. Chem.?2025, 43, 1847-1854.
3. Sun, Jun;?Sun, Yu;?Gu, Yu-Cheng;?Lin, Jin-Hong*;?Xiao, Ji-Chang*?“Barton-Kellogg Olefination of (CF3S)2C=S and Subsequent Cyclopropanation for the Installation of Bulky Bis(trifluoromethylthio)methylene Group” JACS Au?2025, 5, 1039–1050.
4. Yang, Xin-Jun; Lin, Jin-Hong*;?Xiao, Ji-Chang*?“BrCF2CN for photocatalytic cyanodifluoromethylation” Nat. Commun.?2025, 16, 445. doi.org/10.1038/s41467-024-55797-4
5. Wang, Zheng; Lin, Jin-Hong*; Xiao, Ji-Chang*?“Photocatalytic Keto- and Amino-Trifluoromethylation of Alkenes” Org. Lett.?2024,?26,?1980-1984.
6. Shi, Hua-Yi; Hu, Jia-Lu; Zheng, Jian; Cai, Ji; Chen, Hongbin*; Lin, Jin-Hong*; Xiao, Ji-Chang*?“Kilogram-Scale Synthesis of Ph3P+CF2CO2-” Org. Process Res. Dev.?2024, 28, 487-491.
7. Liu, Chao;?Guo, Yong;?Xiao, Ji-Chang*?“The legacy of Prof. Qing-Yun Chen: Organofluorine chemistry” Chem?2024, 10, 7-18.
8. Zhang, Min;?Li, Qiang;?Lin, Jin-Hong;?Xiao, Ji-Chang*?“Difluoroalkylation/Lactonization of Alkenes with BrCF2CO2K via Photoredox Catalysis: Access to α,α-Difluoro-γ-lactones” Chin. J. Chem.?2023, 41, 2819-2824.
9. Yang, Yi-Fei;?Xiao, Fang;?Lin, Jin-Hong;?Xiao, Ji-Chang*?“The Shuttle of Sulfur Dioxide: Iridium/Copper-Cocatalyzed Trifluoromethylfluorosulfonylation of Alkenes” Adv. Synth. Catal.?2023, 365, 301-306.
10. Yu, Donghai; An, Huaying; Du, Ruobing; Li, Linyan; Xu, Shengming; Xiao, Jichang* “A Highly Efficient Heavy Rare Earths Extractant——P227” J. Chin. Soc. Rare Earths?2022, 40, 976-987.
11. Zhang, Feng-Xu; Lin, Jin-Hong*; Xiao, Ji-Chang*. “Difluoromethylsulfonyl Imidazolium Salt for Difluoromethylation of Alkenes” Org. Lett.?2022, 24, 7611-7616.
12. Zhang, Wei;?Deng, Xiaoyun;?Zhang, Feng-Xu; Lin, Jin-Hong; Xiao, Ji-Chang*; Liang, Steven H.*. “Synthesis and?18F Labeling of Alkenyl Sulfonyl Fluorides via an Unconventional Elimination Pathway” Org. Lett.?2022, 24, 4992-4997.
13. Yang, Yi-Fei; Lin, Jin-Hong*; Xiao, Ji-Chang*?“Starting from Styrene: A Unified Protocol for Hydrotrifluoromethylation of Diversified Alkenes”?Org. Lett.?2021, 23, 9277-9282.
14. Zhang, Min; Lin, Jin-Hong; Xiao, Ji-Chang*?“A Readily Available Trifluoromethylation Reagent and Its Difunctionalization of Alkenes”?Org. Lett. 2021,?23, 6079-6083.
15. Zhang, Min; Lin, Jin-Hong; Jin, Chuan-Ming*; Xiao, Ji-Chang*?“Difluorocarbene-based cyanodifluoromethylation?of alkenes induced by a dual-functional?Cu-catalyst”?Chem. Commun.?2021, 57, 2649–2652.
16. Xu, Zhi-Wei;?Zhang, Wei; Lin, Jin-Hong*;?Jin, Chuan-Ming*; Xiao, Ji-Chang*?“Pd-catalyzed transfer of difluorocarbene for three component cross-coupling”?Chin. J. Chem.?2020, 38, 1647-1650.
17. Zhang, Wei;?Gu, Yu-Cheng;?Lin, Jin-Hong*; Xiao, Ji-Chang*?“Dehydroxylative Fluorination of Tertiary Alcohols”?Org. Lett.?2020, 22, 6642-6646.
18. Lin, Jin-Hong;?Xiao, Ji-Chang*?“Fluorinated Ylides/Carbenes and Related Intermediates from Phosphonium/Sulfonium Salts”?Acc. Chem. Res.?2020, 53, 1498-1510.
19. Zhang, Wei;?Lin, Jin-Hong;?Zhang, Pengfei*;?Xiao, Ji-Chang*?“A convenient reagent for the conversion of?aldoximes into nitriles and isonitriles”?Chem. Commun.?2020, 56, 6221-6224.
10. Zhang, Wei;?Lin, Jin-Hong; Wu, Wenfeng*;?Cao, Yu-Cai; Xiao, Ji-Chang* “Dehydroxylative trifluoromethylthiolation, trifluoromethylation, and difluoromethylation of alcohols” Chin. J. Chem. 2020, 38, 169-172.
21. Yu, Jiao; Lin, Jin-Hong; Yu, Donghai; Du, Ruobing; Xiao, Ji-Chang*?“Oxidation of difluorocarbene and subsequent trifluoromethoxylation”?Nat. Commun.?2019, 10: 5362 doi: 10.1038/s41467-019-13359-z?
22. Zhang, Min; Lin, Jin-Hong; Xiao, Ji-Chang*?“Photocatalyzed Cyanodifluoromethylation of Alkenes”?Angew. Chem. Int. Ed.?2019, 58, 6079-6083.
23. Liu, Zhuo;?Long, Jin;?Xiao, Xuan;?Lin, Jin-Hong*;?Zheng, Xing*;?Xiao, Ji-Chang*;?Cao, Yu-Cai?“Ph3P+CF2CO2-?as an F-?and :CF2?source for trifluoromethylthiolation of alkyl halides”?Chin. Chem. Lett.?2019, 30, 714-716.
24. Chen, Xin-Lei;?Zhou, Sheng-Hua; Lin, Jin-Hong; Deng, Qing-Hai*;?Xiao, Ji-Chang*?“Difluorocarbene-derived trifluoromethylselenolation?of?benzyl?halides”?Chem. Commun.?2019, 55, 1410-1413.
25. Zhang, Wei; Chen, Jia; Lin, Jin-Hong*; Xiao, Ji-Chang*; Gu, Yu-Cheng “Rapid Dehydroxytrifluoromethoxylation of Alcohols” iScience?2018, 5, 110-117.
26. Chen, Jia; Lin, Jin-Hong; Xiao, Ji-Chang*?“Dehydroxylation of alcohols for nucleophilic substitution” Chem. Commun.?2018, 54, 7034-7037.
27. Chen, Jia; Lin, Jin-Hong; Xiao, Ji-Chang*?“Halogenation through Deoxygenation of Alcohols and Aldehydes” Org. Lett.?2018, 20, 3061-3064.
28. Yu, Jiao; Lin, Jin-Hong*; Xiao, Ji-Chang*?“Reaction of Thiocarbonyl Fluoride Generated from Difluorocarbene with Amines”?Angew. Chem. Int. Ed.?2017, 56, 16669-16673.
29. Duan, Yaya; Lin, Jin-Hong*; Xiao, Ji-Chang*; Gu, Yu-Cheng?“Difluoromethylcarbene for iron-catalyzed cyclopropanation”?Chem. Commun.?2017, 53,?3870-3873.
30. Zheng, Jian; Cheng, Ran; Lin, Jin-Hong; Yu, Dong-Hai; Ma, Longle; Jia, Lina; Zhang, Lan; Wang, Lu; Xiao, Ji-Chang*; Liang, Steven H.*?“An Unconventional Mechanistic Insight into SCF3?Formation from Difluorocarbene: Preparation of 18F-Labeled α-SCF3?Carbonyl Compounds”?Angew. Chem. Int. Ed.?2017, 56,?3196-3200.
31. Deng, Xiao-Yun; Lin, Jin-Hong; Xiao, Ji-Chang*?“Pd-Catalyzed Transfer of Difluorocarbene”?Org.?Lett.?2016,?18,?4384-4387.
32. Deng, Zuyong; Lin, Jin-Hong; Cai, Ji; Xiao, Ji-Chang*?“Direct Nucleophilic Difluoromethylation of Carbonyl Compounds”?Org. Lett.?2016, 18, 3206-3209.
33. Duan, Yaya;?Lin, Jin-Hong*;?Xiao, Ji-Chang*;?Gu, Yu-Cheng “A Trifluoromethylcarbene Source”?Org. Lett.?2016, 18, 2471-2474.
34. Yu, Donghai; Du, Ruobing; Xiao, Ji-Chang*?“pKa?Prediction for Acidic Phosphorus-Containing Compounds Using Multiple Linear Regression with Computational Descriptors”?J. Comput. Chem.?2016, 37, 1668-1671.
35. Ji, Yun-Long; Luo, Jia-Jia; Lin, Jin-Hong; Xiao, Ji-Chang*; Gu, Yu-Cheng “Cu-catalyzed C-H trifluoromethylation of?3-arylprop-1-ynes for the selective construction of allenic Csp2-CF3?and propargyl Csp3-CF3?bonds”?Org. Lett.?2016, 18, 1000-1003.
36. Deng, Zuyong; Lin, Jin-Hong; Xiao, Ji-Chang*?“Nucleophilic arylation with tetraarylphosphonium salts”?Nat. Commun.?2016, 7: 10337 doi: 10.1038/ncomms10337.
37. Zheng, Jian; Lin, Jin-Hong; Yu, Liu-Ying; Wei, Yun; Zheng, Xing; Xiao, Ji-Chang*?“Cross-Coupling between difluorocarbene and carbene-derived in-termediates generated from diazocompounds for the synthesis of gem-difluoroolefins”?Org. Lett.?2015, 17, 6150-6153.
38. Zheng, Jian; Wang, Lu; Lin, Jin-Hong; Xiao, Ji-Chang*; Liang, Steven H.*?“Difluorocarbene-Derived Trifluoromethylthiolation and [18F]Trifluoromethylthiolation of Aliphatic Electrophiles”?Angew.?Chem.?Int.?Ed.?2015,?54, 13236-13240.
39. Duan, Yaya; Zhou, Bin; Lin, Jin-Hong; Xiao, Ji-Chang*?“Diastereoselective Johnson-Corey-Chaykovsky trifluoroethylidenation”?Chem.?Commun.?2015,?51,?13127-13130.
40. Deng, Xiao-Yun; Lin, Jin-Hong; Zheng, Jian; Xiao, Ji-Chang*?“Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylation”?Chem. Commun.?2015,?51,?8805-8808.
41. Zheng, Jian; Lin, Jin-Hong; Deng, Xiao-Yun; Xiao, Ji-Chang*?“1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)-Promoted Decomposition?of Difluorocarbene and the Subsequent Trifluoromethylation”?Org. Lett.?2015, 17, 532-535.
42. Zhang, Cheng-Pan; Chen, Qing-Yun; Guo, Yong; Xiao, Ji-Chang*; Gu, Yu-Cheng. “Difluoromethylation and Trifluoromethylation Reagents Derived from Tetrafluoroethane β-Sultone: Synthesis, Reactivity and Applications”?Coord. Chem. Rev.?2014, 261, 28-72.
43. Zhang, Cheng-Pan; Chen, Qing-Yun; Guo, Yong*; Xiao, Ji-Chang*; Gu, Yu-Cheng “Progress in fluoroalkylation of organic compounds via sulfinatodehalogenation initiation system”?Chem. Soc. Rev.?2012, 41, 4536-4559.
44. Zhang, Cheng-Pan;?Wang, Zong-Ling;?Chen, Qing-Yun;?Zhang, Chun-Tao;?Gu, Yu-Cheng;?Xiao, Ji-Chang*. “Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds?by Trifluoromethyl Sulfonium Salts”?Angew. Chem. Int. Ed.?2011, 50, 1896-1900.
